Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes

Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes

This is another mouse-model study that examines neurodevelopmental impairment in association with both the POGZ gene as well as the ADNP gene that causes ADNP syndrome (also known as Helsmoortel-VanDerAa Syndrome). While the foundation wasn’t directly involved in this study, it was authored in part by a member of our medical advisory board, Dr. Eirene Markenscoff-Papadimitriou.